5WDJ

CRYSTAL STRUCTURE OF MYELOPEROXIDASE SUBFORM C (MPO) COMPLEX WITH COMPOUND-6 AKA 7-(BENZYLOXY)-1H-[1,2, 3]TRIAZOLO[4,5-D]PYRIMIDIN-5-AMINE

5WDJ の概要

• エントリーDOI: 10.2210/pdb5wdj/pdb
• 分子名称: Myeloperoxidase, alpha-L-fucopyranose, alpha-D-mannopyranose, ... (12 entities in total)
• 機能のキーワード: myeloperoxidase, metal binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 135605.64

構造登録者

Khan, J.A. (登録日: 2017-07-05, 公開日: 2018-04-18, 最終更新日: 2020-07-29)

• 主引用文献: Duclos, F.,Abell, L.M.,Harden, D.G.,Pike, K.,Nowak, K.,Locke, G.A.,Duke, G.J.,Liu, X.,Fernando, G.,Shaw, S.A.,Vokits, B.P.,Wurtz, N.R.,Viet, A.,Valente, M.N.,Stachura, S.,Sleph, P.,Khan, J.A.,Gao, J.,Dongre, A.R.,Zhao, L.,Wexler, R.R.,Gordon, D.A.,Kick, E.K.; Triazolopyrimidines identified as reversible myeloperoxidase inhibitors.; Medchemcomm, 8:2093-2099, 2017; PubMed: 30108726; DOI: 10.1039/c7md00268h

実験手法

X-RAY DIFFRACTION (2.4 Å)