5WCH

Crystal structure of the catalytic domain of human USP9X

5WCH の概要

• エントリーDOI: 10.2210/pdb5wch/pdb
• 分子名称: Probable ubiquitin carboxyl-terminal hydrolase FAF-X, ZINC ION, UNKNOWN ATOM OR ION, ... (4 entities in total)
• 機能のキーワード: deubiquitinase, structural genomics, structural genomics consortium, sgc, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 194494.87

構造登録者

Dong, A.,Zhang, Q.,Walker, J.R.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Tong, Y.,Structural Genomics Consortium (SGC) (登録日: 2017-06-30, 公開日: 2018-07-04, 最終更新日: 2024-03-13)

• 主引用文献: Paudel, P.,Zhang, Q.,Leung, C.,Greenberg, H.C.,Guo, Y.,Chern, Y.H.,Dong, A.,Li, Y.,Vedadi, M.,Zhuang, Z.,Tong, Y.; Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X.; Proc. Natl. Acad. Sci. U.S.A., 116:7288-7297, 2019; PubMed: 30914461; DOI: 10.1073/pnas.1815027116

実験手法

X-RAY DIFFRACTION (2.5 Å)