5W8U
Crystal structure of MERS-CoV papain-like protease in complex with the C-terminal domain of human ISG15
Summary for 5W8U
Entry DOI | 10.2210/pdb5w8u/pdb |
Descriptor | ORF1ab, Ubiquitin-like protein ISG15, ZINC ION, ... (6 entities in total) |
Functional Keywords | signaling protein, hydrolase, papain-like protease, isg15 |
Biological source | Human betacoronavirus 2c EMC/2012 More |
Total number of polymer chains | 4 |
Total formula weight | 90826.84 |
Authors | Daczkowski, C.M.,Goodwin, O.Y.,Dzimianski, J.D.,Pegan, S.D. (deposition date: 2017-06-22, release date: 2017-09-27, Last modification date: 2024-04-24) |
Primary citation | Daczkowski, C.M.,Goodwin, O.Y.,Dzimianski, J.V.,Farhat, J.J.,Pegan, S.D. Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus. J. Virol., 91:-, 2017 Cited by PubMed: 28931677DOI: 10.1128/JVI.01067-17 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.411 Å) |
Structure validation
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