5W8U

Crystal structure of MERS-CoV papain-like protease in complex with the C-terminal domain of human ISG15

5W8U の概要

• エントリーDOI: 10.2210/pdb5w8u/pdb
• 分子名称: ORF1ab, Ubiquitin-like protein ISG15, ZINC ION, ... (6 entities in total)
• 機能のキーワード: signaling protein, hydrolase, papain-like protease, isg15
• 由来する生物種: Human betacoronavirus 2c EMC/2012; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 90826.84

構造登録者

Daczkowski, C.M.,Goodwin, O.Y.,Dzimianski, J.D.,Pegan, S.D. (登録日: 2017-06-22, 公開日: 2017-09-27, 最終更新日: 2024-04-24)

• 主引用文献: Daczkowski, C.M.,Goodwin, O.Y.,Dzimianski, J.V.,Farhat, J.J.,Pegan, S.D.; Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus.; J. Virol., 91:-, 2017; PubMed: 28931677; DOI: 10.1128/JVI.01067-17

実験手法

X-RAY DIFFRACTION (2.411 Å)