5W7V

CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril

Summary for 5W7V

Entry DOI	10.2210/pdb5w7v/pdb
EMDB information	8781
Descriptor	TAR DNA-binding protein 43 (1 entity in total)
Functional Keywords	amyloid, steric zipper, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	9
Total formula weight	10885.31
Authors	Guenther, E.L.,Ge, P.,Eisenberg, D.S. (deposition date: 2017-06-20, release date: 2018-03-14, Last modification date: 2024-03-13)
Primary citation	Guenther, E.L.,Ge, P.,Trinh, H.,Sawaya, M.R.,Cascio, D.,Boyer, D.R.,Gonen, T.,Zhou, Z.H.,Eisenberg, D.S. Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nat. Struct. Mol. Biol., 25:311-319, 2018 Cited by PubMed: 29531287 DOI: 10.1038/s41594-018-0045-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation