5W7V
CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril
Summary for 5W7V
Entry DOI | 10.2210/pdb5w7v/pdb |
EMDB information | 8781 |
Descriptor | TAR DNA-binding protein 43 (1 entity in total) |
Functional Keywords | amyloid, steric zipper, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 9 |
Total formula weight | 10885.31 |
Authors | Guenther, E.L.,Ge, P.,Eisenberg, D.S. (deposition date: 2017-06-20, release date: 2018-03-14, Last modification date: 2024-03-13) |
Primary citation | Guenther, E.L.,Ge, P.,Trinh, H.,Sawaya, M.R.,Cascio, D.,Boyer, D.R.,Gonen, T.,Zhou, Z.H.,Eisenberg, D.S. Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nat. Struct. Mol. Biol., 25:311-319, 2018 Cited by PubMed: 29531287DOI: 10.1038/s41594-018-0045-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
Download full validation report