5W6Q
Structural basis for recognition of artificial DNA by an evolved KlenTaq variant
Summary for 5W6Q
Entry DOI | 10.2210/pdb5w6q/pdb |
Descriptor | DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(1W5))-3'), DNA (5'-D(P*GP*(1WA)P*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (4 entities in total) |
Functional Keywords | protein-dna, aegis, unnatural base pair, host-guest system, transferase-dna complex, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Thermus aquaticus More |
Total number of polymer chains | 9 |
Total formula weight | 205700.68 |
Authors | Singh, I.,Georgiadis, M.M. (deposition date: 2017-06-16, release date: 2018-07-18, Last modification date: 2023-10-04) |
Primary citation | Singh, I.,Laos, R.,Hoshika, S.,Benner, S.A.,Georgiadis, M.M. Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide. Nucleic Acids Res., 46:7977-7988, 2018 Cited by PubMed: 29986111DOI: 10.1093/nar/gky552 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.66 Å) |
Structure validation
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