5W6Q

Structural basis for recognition of artificial DNA by an evolved KlenTaq variant

5W6Q の概要

• エントリーDOI: 10.2210/pdb5w6q/pdb
• 分子名称: DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(1W5))-3'), DNA (5'-D(P*GP*(1WA)P*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (4 entities in total)
• 機能のキーワード: protein-dna, aegis, unnatural base pair, host-guest system, transferase-dna complex, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Thermus aquaticus; 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 205700.68

構造登録者

Singh, I.,Georgiadis, M.M. (登録日: 2017-06-16, 公開日: 2018-07-18, 最終更新日: 2023-10-04)

• 主引用文献: Singh, I.,Laos, R.,Hoshika, S.,Benner, S.A.,Georgiadis, M.M.; Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide.; Nucleic Acids Res., 46:7977-7988, 2018; PubMed: 29986111; DOI: 10.1093/nar/gky552

実験手法

X-RAY DIFFRACTION (2.66 Å)