5W6K

Structure of mutant Taq Polymerase incorporating unnatural base pairs Z:P

5W6K の概要

• エントリーDOI: 10.2210/pdb5w6k/pdb
• 分子名称: DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(P*(1WA)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (6 entities in total)
• 機能のキーワード: mutant taq polymerase, unnatural base pairs, aegis, ternary complex, klentaq, binary complex, transferase-dna complex, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Thermus aquaticus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 69068.68

構造登録者

Singh, I.,Georgiadis, M.M. (登録日: 2017-06-16, 公開日: 2018-07-18, 最終更新日: 2023-10-04)

• 主引用文献: Singh, I.,Laos, R.,Hoshika, S.,Benner, S.A.,Georgiadis, M.M.; Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide.; Nucleic Acids Res., 46:7977-7988, 2018; PubMed: 29986111; DOI: 10.1093/nar/gky552

実験手法

X-RAY DIFFRACTION (2.339 Å)