5W5L
Crystal structure of human IgG1-Sigma Fc fragment
5W5L の概要
エントリーDOI | 10.2210/pdb5w5l/pdb |
分子名称 | Immunoglobulin gamma-1 heavy chain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
機能のキーワード | fc, immunoglobulin fold, immune system |
由来する生物種 | Homo sapiens (Human) |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 53163.29 |
構造登録者 | |
主引用文献 | Tam, S.H.,McCarthy, S.G.,Armstrong, A.A.,Somani, S.,Wu, S.J.,Liu, X.,Gervais, A.,Ernst, R.,Saro, D.,Decker, R.,Luo, J.,Gilliland, G.L.,Chiu, M.L.,Scallon, B.J. Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality. Antibodies, 6:-, 2017 Cited by PubMed: 31548527DOI: 10.3390/antib6030012 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.9 Å) |
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