5W4H
X-ray crystallographic structure of a beta-hairpin peptide mimic derived from Abeta 16-36. Synchrotron data set. (ORN)KLV(MEA)FAE(ORN)AIIGLMV.
Summary for 5W4H
Entry DOI | 10.2210/pdb5w4h/pdb |
Descriptor | A-beta 17_36 peptide: ORN-LYS-LEU-VAL-MEA-PHE-ALA-GLU-ORN-ALA-ILE-ILE-GLY-LEU-MET-VAL (2 entities in total) |
Functional Keywords | amyloid, oligomer, alzheimer's, trimer, protein fibril, de novo protein |
Biological source | Homo sapiens |
Total number of polymer chains | 3 |
Total formula weight | 5382.81 |
Authors | Kreutzer, A.G.,Spencer, R.K.,Nowick, J.S. (deposition date: 2017-06-11, release date: 2017-11-22, Last modification date: 2023-10-04) |
Primary citation | Kreutzer, A.G.,Spencer, R.K.,McKnelly, K.J.,Yoo, S.,Hamza, I.L.,Salveson, P.J.,Nowick, J.S. A Hexamer of a Peptide Derived from A beta 16-36. Biochemistry, 56:6061-6071, 2017 Cited by PubMed: 29028351DOI: 10.1021/acs.biochem.7b00831 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.718 Å) |
Structure validation
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