5W41
Zika MR766 NLS in complex with Importin alpha subunit-1
Summary for 5W41
Entry DOI | 10.2210/pdb5w41/pdb |
Descriptor | Importin subunit alpha-1, ZIKA MR766 NLS (3 entities in total) |
Functional Keywords | zika, nuclear transport, importin, karyopherin, virus, mr766, viral protein-protein binding complex, viral protein/protein binding |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 59940.96 |
Authors | Jeffress, S.,Smith, K.M.,Forwood, J.K. (deposition date: 2017-06-08, release date: 2018-06-13, Last modification date: 2023-10-04) |
Primary citation | Ng, I.H.W.,Chan, K.,Tan, M.J.A.,Gwee, C.P.,Smith, K.M.,Jeffress, S.J.,Saw, W.G.,Swarbrick, C.M.D.,Watanabe, S.,Jans, D.,Gruber, G.,Forwood, J.K.,Vasudevan, S.G. Zika virus NS5 forms supramolecular nuclear bodies that sequester importin alpha and modulate the host immune and pro-inflammatory response in neuronal cells. ACS Infect Dis, 2019 Cited by PubMed: 30848123DOI: 10.1021/acsinfecdis.8b00373 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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