5W38

1.80A resolution structure of human IgG3 Fc (N392K)

Summary for 5W38

• Entry DOI: 10.2210/pdb5w38/pdb
• Descriptor: Immunoglobulin heavy constant gamma 3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, ... (4 entities in total)
• Functional Keywords: immunoglobulin g3, glycosylation, fc receptor, protein a, immune system
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted : P01860
• Total number of polymer chains: 2
• Total formula weight: 51809.67

Authors

Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Shah, I.,Tolbert, T.J. (deposition date: 2017-06-07, release date: 2017-10-18, Last modification date: 2023-10-04)

• Primary citation: Shah, I.S.,Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Tolbert, T.J.; Structural characterization of the Man5 glycoform of human IgG3 Fc.; Mol. Immunol., 92:28-37, 2017; PubMed: 29031045; DOI: 10.1016/j.molimm.2017.10.001

Experimental method

X-RAY DIFFRACTION (1.8 Å)