5W27
Crystal structure of TnmS3 in complex with tiancimycin (TNM B)
Summary for 5W27
Entry DOI | 10.2210/pdb5w27/pdb |
Related | 5W29 |
Descriptor | Glyoxalase/bleomycin resisance protein/dioxygenase, methyl (2E)-3-[(1aS,11S,11aS,14Z,18R)-3,18-dihydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]but-2-enoate (3 entities in total) |
Functional Keywords | glyoxalase/bleomycin resistance protein/dioxygenase superfamily, structural genomics, psi-biology, midwest center for structural genomics, mcsg, enzyme discovery for natural product biosynthesis, natpro, lyase, biosynthetic protein, tiancimycin-binding protein |
Biological source | Streptomyces sp. CB03234 |
Total number of polymer chains | 2 |
Total formula weight | 32017.58 |
Authors | Chang, C.Y.,Chang, C.,Nocek, B.,Rudolf, J.D.,Joachimiak, A.,Phillips Jr., G.N.,SHen, B.,Enzyme Discovery for Natural Product Biosynthesis (NatPro),Midwest Center for Structural Genomics (MCSG) (deposition date: 2017-06-05, release date: 2018-06-06, Last modification date: 2023-10-04) |
Primary citation | Chang, C.Y.,Chang, C.,Nocek, B.,Rudolf, J.D.,Joachimiak, A.,Phillips, G.N.,SHen, B.,Enzyme Discovery for Natural Product Biosynthesis (NatPro),Midwest Center for Structural Genomics (MCSG) Crystal structure of TnmS3 in complex with tiancimycin (TNM B) To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report