5W23

Crystal Structure of RSV F in complex with 5C4 Fab

Summary for 5W23

• Entry DOI: 10.2210/pdb5w23/pdb
• Descriptor: Fusion glycoprotein F0, 5C4 Fab heavy chain, 5C4 Fab light chain, ... (4 entities in total)
• Functional Keywords: rsv, complex, fab, antibody, neutralizing antibody, viral protein-immune system complex, viral protein/immune system
• Biological source: Human respiratory syncytial virus A; More
• Cellular location: Virion membrane; Single-pass type I membrane protein: P03420
• Total number of polymer chains: 9
• Total formula weight: 350086.04

Authors

Battles, M.B.,McLellan, J.S. (deposition date: 2017-06-05, release date: 2017-12-06, Last modification date: 2023-10-04)

• Primary citation: Tian, D.,Battles, M.B.,Moin, S.M.,Chen, M.,Modjarrad, K.,Kumar, A.,Kanekiyo, M.,Graepel, K.W.,Taher, N.M.,Hotard, A.L.,Moore, M.L.,Zhao, M.,Zheng, Z.Z.,Xia, N.S.,McLellan, J.S.,Graham, B.S.; Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein.; Nat Commun, 8:1877-1877, 2017; PubMed: 29187732; DOI: 10.1038/s41467-017-01858-w

Experimental method

X-RAY DIFFRACTION (3.4 Å)