5W23
Crystal Structure of RSV F in complex with 5C4 Fab
Summary for 5W23
Entry DOI | 10.2210/pdb5w23/pdb |
Descriptor | Fusion glycoprotein F0, 5C4 Fab heavy chain, 5C4 Fab light chain, ... (4 entities in total) |
Functional Keywords | rsv, complex, fab, antibody, neutralizing antibody, viral protein-immune system complex, viral protein/immune system |
Biological source | Human respiratory syncytial virus A More |
Cellular location | Virion membrane; Single-pass type I membrane protein: P03420 |
Total number of polymer chains | 9 |
Total formula weight | 350086.04 |
Authors | Battles, M.B.,McLellan, J.S. (deposition date: 2017-06-05, release date: 2017-12-06, Last modification date: 2023-10-04) |
Primary citation | Tian, D.,Battles, M.B.,Moin, S.M.,Chen, M.,Modjarrad, K.,Kumar, A.,Kanekiyo, M.,Graepel, K.W.,Taher, N.M.,Hotard, A.L.,Moore, M.L.,Zhao, M.,Zheng, Z.Z.,Xia, N.S.,McLellan, J.S.,Graham, B.S. Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein. Nat Commun, 8:1877-1877, 2017 Cited by PubMed: 29187732DOI: 10.1038/s41467-017-01858-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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