5W07

CRYSTAL STRUCTURE OF THE INHA FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AN12855, EBSI 4333.

5W07 の概要

• エントリーDOI: 10.2210/pdb5w07/pdb
• 分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], (~{N}~{E})-~{N}-[[2-[[2-ethylsulfonyl-1,1-bis(oxidanyl)-3,4-dihydro-2,3,1$l^{4}-benzodiazaborinin-7-yl]oxy]-5-(trifluoromethyl)phenyl]methylidene]hydroxylamine (3 entities in total)
• 機能のキーワード: inha, enoyl-acyl reductase, tuberculosis, oxidoreductase
• 由来する生物種: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29297.27

構造登録者

Abendroth, J.,Edwards, T.E.,Lorimer, D. (登録日: 2017-05-30, 公開日: 2018-06-13, 最終更新日: 2024-03-13)

• 主引用文献: Alley, M.R.K.,Zhou, Y.; Discovery of a cofactor-independent inhibitor of Mycobacterium tuberculosis InhA; To Be Published,

実験手法

X-RAY DIFFRACTION (2.65 Å)