5VZR

Crystal Structure of MERS-CoV neutralizing antibody G4 Fab

Summary for 5VZR

Entry DOI	10.2210/pdb5vzr/pdb
Descriptor	G4 antibody heavy chain, G4 antibody light chain, GLYCEROL, ... (4 entities in total)
Functional Keywords	immune system, antibody, neutralizing
Biological source	Mus musculus (mouse) More
Total number of polymer chains	4
Total formula weight	98417.47
Authors	Wang, N.,Wrapp, D.,McLellan, J.S. (deposition date: 2017-05-29, release date: 2017-08-30, Last modification date: 2023-10-04)
Primary citation	Pallesen, J.,Wang, N.,Corbett, K.S.,Wrapp, D.,Kirchdoerfer, R.N.,Turner, H.L.,Cottrell, C.A.,Becker, M.M.,Wang, L.,Shi, W.,Kong, W.P.,Andres, E.L.,Kettenbach, A.N.,Denison, M.R.,Chappell, J.D.,Graham, B.S.,Ward, A.B.,McLellan, J.S. Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proc. Natl. Acad. Sci. U.S.A., 114:E7348-E7357, 2017 Cited by PubMed: 28807998 DOI: 10.1073/pnas.1707304114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.57 Å)

Structure validation