5VT4

Sco GlgEI-V279S in complex with a pyrolidene-based methyl-phosphonate compound

5VT4 の概要

• エントリーDOI: 10.2210/pdb5vt4/pdb
• 関連するPDBエントリー: 5VSJ
• 分子名称: Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1, {[(2R,3R,4R,5R)-3-(alpha-D-glucopyranosyloxy)-4-hydroxy-2,5-bis(hydroxymethyl)pyrrolidin-1-yl]methyl}phosphonic acid (3 entities in total)
• 機能のキーワード: streptomyces coelicolor, maltosyltransferase, transition state analogue, alpha-1, 4-glucan, transferase
• 由来する生物種: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 298393.81

構造登録者

Petit, C.,Ronning, D.R.,Lindenberger, J.J. (登録日: 2017-05-15, 公開日: 2017-06-07, 最終更新日: 2023-10-04)

• 主引用文献: Veleti, S.K.,Petit, C.,Ronning, D.R.,Sucheck, S.J.; Zwitterionic pyrrolidene-phosphonates: inhibitors of the glycoside hydrolase-like phosphorylase Streptomyces coelicolor GlgEI-V279S.; Org. Biomol. Chem., 15:3884-3891, 2017; PubMed: 28422240; DOI: 10.1039/c7ob00388a

実験手法

X-RAY DIFFRACTION (3.205 Å)