5VT2
Crystal structure of growth differentiation factor
Summary for 5VT2
Entry DOI | 10.2210/pdb5vt2/pdb |
Descriptor | Growth/differentiation factor 15, 1,2-ETHANEDIOL (3 entities in total) |
Functional Keywords | tgf-beta family, signaling protein |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted : Q99988 |
Total number of polymer chains | 2 |
Total formula weight | 24978.90 |
Authors | |
Primary citation | Xiong, Y.,Walker, K.,Min, X.,Hale, C.,Tran, T.,Komorowski, R.,Yang, J.,Davda, J.,Nuanmanee, N.,Kemp, D.,Wang, X.,Liu, H.,Miller, S.,Lee, K.J.,Wang, Z.,Veniant, M.M. Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys. Sci Transl Med, 9:-, 2017 Cited by PubMed: 29046435DOI: 10.1126/scitranslmed.aan8732 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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