5VSL

Crystal structure of viperin with bound [4Fe-4S] cluster and S-adenosylhomocysteine (SAH)

5VSL の概要

関連するPDBエントリー5VSM
分子名称Radical S-adenosyl methionine domain-containing protein 2, IRON/SULFUR CLUSTER, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
機能のキーワードradical, s-adenosylmethionine, iron-sulfur cluster, antiviral response, antiviral protein
由来する生物種Mus musculus (Mouse)
細胞内の位置Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side Q8CBB9
ポリマー鎖数2
分子量合計75093.63
構造登録者
Fenwick, M.K.,Li, Y.,Cresswell, P.,Modis, Y.,Ealick, S.E. (登録日: 2017-05-11, 公開日: 2017-06-14, 最終更新日: 2017-09-27)
主引用文献
Fenwick, M.K.,Li, Y.,Cresswell, P.,Modis, Y.,Ealick, S.E.
Structural studies of viperin, an antiviral radical SAM enzyme.
Proc. Natl. Acad. Sci. U.S.A., 114:6806-6811, 2017
PubMed: 28607080 (主引用文献が同じPDBエントリー)
DOI: 10.1073/pnas.1705402114
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.972 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.200202.0%3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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