5VR2
mouse myocilin leucine zipper C-terminal 7 heptad repeat
Summary for 5VR2
Entry DOI | 10.2210/pdb5vr2/pdb |
Descriptor | Myocilin (2 entities in total) |
Functional Keywords | coiled coil, disulfide bond, extracellular matrix, trabecular meshwork, leucine zipper, signaling protein |
Biological source | Mus musculus (Mouse) |
Cellular location | Secreted . Myocilin, C-terminal fragment: Secreted . Myocilin, N-terminal fragment: Endoplasmic reticulum: O70624 |
Total number of polymer chains | 4 |
Total formula weight | 23834.03 |
Authors | Lieberman, R.L.,Hill, S.E. (deposition date: 2017-05-10, release date: 2017-11-08, Last modification date: 2017-11-15) |
Primary citation | Hill, S.E.,Nguyen, E.,Donegan, R.K.,Patterson-Orazem, A.C.,Hazel, A.,Gumbart, J.C.,Lieberman, R.L. Structure and Misfolding of the Flexible Tripartite Coiled-Coil Domain of Glaucoma-Associated Myocilin. Structure, 25:1697-1707.e5, 2017 Cited by PubMed: 29056483DOI: 10.1016/j.str.2017.09.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.922 Å) |
Structure validation
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