5VR2

mouse myocilin leucine zipper C-terminal 7 heptad repeat

5VR2 の概要

• エントリーDOI: 10.2210/pdb5vr2/pdb
• 分子名称: Myocilin (2 entities in total)
• 機能のキーワード: coiled coil, disulfide bond, extracellular matrix, trabecular meshwork, leucine zipper, signaling protein
• 由来する生物種: Mus musculus (Mouse)
• 細胞内の位置: Secreted . Myocilin, C-terminal fragment: Secreted . Myocilin, N-terminal fragment: Endoplasmic reticulum: O70624
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 23834.03

構造登録者

Lieberman, R.L.,Hill, S.E. (登録日: 2017-05-10, 公開日: 2017-11-08, 最終更新日: 2017-11-15)

• 主引用文献: Hill, S.E.,Nguyen, E.,Donegan, R.K.,Patterson-Orazem, A.C.,Hazel, A.,Gumbart, J.C.,Lieberman, R.L.; Structure and Misfolding of the Flexible Tripartite Coiled-Coil Domain of Glaucoma-Associated Myocilin.; Structure, 25:1697-1707.e5, 2017; PubMed: 29056483; DOI: 10.1016/j.str.2017.09.008

実験手法

X-RAY DIFFRACTION (1.922 Å)