5VOS
VGSNKGAIIGL from Amyloid Beta determined by MicroED
Summary for 5VOS
Entry DOI | 10.2210/pdb5vos/pdb |
Related | 5KNZ |
EMDB information | 8720 |
Descriptor | Amyloid beta A4 protein (2 entities in total) |
Functional Keywords | amyloid, steric zipper, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 1029.21 |
Authors | Rodriguez, J.A.,Sawaya, M.R.,Cascio, D.,Eisenberg, D.S.,Griner, S.L.,Gonen, T. (deposition date: 2017-05-03, release date: 2018-01-03, Last modification date: 2024-03-13) |
Primary citation | Krotee, P.,Griner, S.L.,Sawaya, M.R.,Cascio, D.,Rodriguez, J.A.,Shi, D.,Philipp, S.,Murray, K.,Saelices, L.,Lee, J.,Seidler, P.,Glabe, C.G.,Jiang, L.,Gonen, T.,Eisenberg, D.S. Common fibrillar spines of amyloid-beta and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors. J. Biol. Chem., 293:2888-2902, 2018 Cited by PubMed: 29282295DOI: 10.1074/jbc.M117.806109 PDB entries with the same primary citation |
Experimental method | ELECTRON CRYSTALLOGRAPHY (1.42 Å) |
Structure validation
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