5VN3
Cryo-EM model of B41 SOSIP.664 in complex with soluble CD4 (D1-D2) and fragment antigen binding variable domain of 17b
Summary for 5VN3
Entry DOI | 10.2210/pdb5vn3/pdb |
Related | 5vn8 |
EMDB information | 8713 8714 8715 8716 8717 |
Descriptor | 17b Fab light chain, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | viral fusion, hiv-1, envelope glycoprotein, cd4 receptor binding, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 15 |
Total formula weight | 456059.35 |
Authors | Ozorowski, G.,Pallesen, J.,Ward, A.B. (deposition date: 2017-04-28, release date: 2017-07-12, Last modification date: 2020-07-29) |
Primary citation | Ozorowski, G.,Pallesen, J.,de Val, N.,Lyumkis, D.,Cottrell, C.A.,Torres, J.L.,Copps, J.,Stanfield, R.L.,Cupo, A.,Pugach, P.,Moore, J.P.,Wilson, I.A.,Ward, A.B. Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike. Nature, 547:360-363, 2017 Cited by PubMed: 28700571DOI: 10.1038/nature23010 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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