5VDB
Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 3
Summary for 5VDB
Entry DOI | 10.2210/pdb5vdb/pdb |
Related | 4L8A 5VD6 |
Descriptor | acetyltransferase PA4794, SULFATE ION, (3R,5S,9R,26S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,20-trioxo-26-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15,21-triaza-3,5-diphosphaheptacosan-27-oic acid 3,5-dioxide (non-preferred name), ... (4 entities in total) |
Functional Keywords | gnat, acetyltransferase, bisubstrate inhibitor, structural genomics, psi-biology, midwest center for structural genomics, mcsg, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
Total number of polymer chains | 1 |
Total formula weight | 19608.79 |
Authors | Majorek, K.A.,Joachimiak, A.,Minor, W.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2017-04-01, release date: 2017-07-26, Last modification date: 2023-10-04) |
Primary citation | Reidl, C.,Majorek, K.A.,Dang, J.,Tran, D.,Jew, K.,Law, M.,Payne, Y.,Minor, W.,Becker, D.P.,Kuhn, M.L. Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases. FEBS Lett., 591:2348-2361, 2017 Cited by PubMed: 28703494DOI: 10.1002/1873-3468.12753 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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