5V7U

Cyrstal structure of anti-Tau antibody CBTAU-22.1 Fab

Summary for 5V7U

• Entry DOI: 10.2210/pdb5v7u/pdb
• Related: 5V7R
• Descriptor: CBTAU-22.1 Fab light chain, CBTAU-22.1 Fab heavy chain, SULFATE ION, ... (4 entities in total)
• Functional Keywords: antibody, fab, tau protein, alzheimer's disease, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 48173.88

Authors

Zhu, X.,Zhang, H.,Wilson, I.A. (deposition date: 2017-03-20, release date: 2017-04-12, Last modification date: 2023-10-04)

• Primary citation: Pascual, G.,Wadia, J.S.,Zhu, X.,Keogh, E.,Kukrer, B.,van Ameijde, J.,Inganas, H.,Siregar, B.,Perdok, G.,Diefenbach, O.,Nahar, T.,Sprengers, I.,Koldijk, M.H.,der Linden, E.C.,Peferoen, L.A.,Zhang, H.,Yu, W.,Li, X.,Wagner, M.,Moreno, V.,Kim, J.,Costa, M.,West, K.,Fulton, Z.,Chammas, L.,Luckashenak, N.,Fletcher, L.,Holland, T.,Arnold, C.,Anthony Williamson, R.,Hoozemans, J.J.,Apetri, A.,Bard, F.,Wilson, I.A.,Koudstaal, W.,Goudsmit, J.; Immunological memory to hyperphosphorylated tau in asymptomatic individuals.; Acta Neuropathol., 133:767-783, 2017; PubMed: 28341999; DOI: 10.1007/s00401-017-1705-y

Experimental method

X-RAY DIFFRACTION (1.64 Å)