5V7S

Crystal structure of Influenza A virus matrix protein M1 (NLS-88E, pH 6.2)

Summary for 5V7S

Related5V6G 5V7B 5V8A
DescriptorMatrix protein 1, PHOSPHATE ION (3 entities in total)
Functional Keywordsinfluenza a, matrix protein, nls-88e mutant, ph 6.2, viral protein
Biological sourceInfluenza A virus (strain A/Wilson-Smith/1933 H1N1)
Cellular locationVirion membrane ; Peripheral membrane protein ; Cytoplasmic side  P05777
Total number of polymer chains3
Total molecular weight57399.87
Authors
Musayev, F.N.,Safo, M.K.,Althufairi, B.,Desai, U.R.,Xie, H.,Mosier, P.D.,Chiang, M.-J.,Zhou, Q. (deposition date: 2017-03-20, release date: 2017-04-12, Last modification date: 2017-12-20)
Primary citation
Chiang, M.J.,Musayev, F.N.,Kosikova, M.,Lin, Z.,Gao, Y.,Mosier, P.D.,Althufairi, B.,Ye, Z.,Zhou, Q.,Desai, U.R.,Xie, H.,Safo, M.K.
Maintaining pH-dependent conformational flexibility of M1 is critical for efficient influenza A virus replication.
Emerg Microbes Infect, 6:e108-e108, 2017
PubMed: 29209052 (PDB entries with the same primary citation)
DOI: 10.1038/emi.2017.96
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.316131.9%6.8%5.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution