5V6Q

Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from Sinorhizobium meliloti in complex with NADP and malonate

Summary for 5V6Q

Entry DOI	10.2210/pdb5v6q/pdb
Related	5J23 5UOG 5V72
Descriptor	NADPH-dependent glyoxylate/hydroxypyruvate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, MALONIC ACID, ... (5 entities in total)
Functional Keywords	nadph-dependent glyoxylate/hydroxypyruvate reductase, nadp, nysgrc, sinorhizobium meliloti, structural genomics, psi-biology, new york structural genomics research consortium, oxidoreductase
Biological source	Rhizobium meliloti (strain 1021) (Ensifer meliloti)
Total number of polymer chains	4
Total formula weight	140892.82
Authors	Shabalin, I.G.,Handing, K.B.,Miezaniec, A.P.,Gasiorowska, O.A.,Bonanno, J.,Almo, S.C.,Minor, W.,New York Structural Genomics Research Consortium (NYSGRC) (deposition date: 2017-03-17, release date: 2017-03-29, Last modification date: 2023-10-04)
Primary citation	Kutner, J.,Shabalin, I.G.,Matelska, D.,Handing, K.B.,Gasiorowska, O.,Sroka, P.,Gorna, M.W.,Ginalski, K.,Wozniak, K.,Minor, W. Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies. Biochemistry, 57:963-977, 2018 Cited by PubMed: 29309127 DOI: 10.1021/acs.biochem.7b01137 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation