5V6J

Glycan binding protein Y3 from mushroom Coprinus comatus possesses anti-leukemic activity

Summary for 5V6J

• Entry DOI: 10.2210/pdb5v6j/pdb
• Related: 5V6I
• Descriptor: TMV resistance protein Y3, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID (3 entities in total)
• Functional Keywords: glycan binding protein, lectin, sugar binding protein
• Biological source: Coprinus comatus (Shaggy mane)
• Total number of polymer chains: 4
• Total formula weight: 49731.20

Authors

Li, K.,Zhang, P.,Gang, Y.,Xia, C.,Polston, J.E.,Li, G.,Li, S.,Lin, Z.,Yang, L.-J.,Bruner, S.D.,Ding, Y. (deposition date: 2017-03-16, release date: 2017-08-16, Last modification date: 2017-09-06)

• Primary citation: Zhang, P.,Li, K.,Yang, G.,Xia, C.,Polston, J.E.,Li, G.,Li, S.,Lin, Z.,Yang, L.J.,Bruner, S.D.,Ding, Y.; Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity.; Proc. Natl. Acad. Sci. U.S.A., 114:8980-8985, 2017; PubMed: 28784797; DOI: 10.1073/pnas.1706894114

Experimental method

X-RAY DIFFRACTION (1.18 Å)