5V6I

Glycan binding protein Y3 from mushroom Coprinus comatus possesses anti-leukemic activity - Pt derivative

5V6I の概要

• エントリーDOI: 10.2210/pdb5v6i/pdb
• 関連するPDBエントリー: 5V6J
• 分子名称: TMV resistance protein Y3, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, PLATINUM (II) ION, ... (5 entities in total)
• 機能のキーワード: glycan binding protein, lectin, sugar binding protein
• 由来する生物種: Coprinus comatus (Shaggy mane)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26071.35

構造登録者

Li, K.,Zhang, P.,Gang, Y.,Xia, C.,Polston, J.E.,Li, G.,Li, S.,Lin, Z.,Yang, L.-J.,Bruner, S.D.,Ding, Y. (登録日: 2017-03-16, 公開日: 2017-08-16, 最終更新日: 2020-01-01)

• 主引用文献: Zhang, P.,Li, K.,Yang, G.,Xia, C.,Polston, J.E.,Li, G.,Li, S.,Lin, Z.,Yang, L.J.,Bruner, S.D.,Ding, Y.; Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity.; Proc. Natl. Acad. Sci. U.S.A., 114:8980-8985, 2017; PubMed: 28784797; DOI: 10.1073/pnas.1706894114

実験手法

X-RAY DIFFRACTION (1.7 Å)