5V4R
Crystal structure of LARP1-unique domain DM15 bound to m7GTP
Summary for 5V4R
Entry DOI | 10.2210/pdb5v4r/pdb |
Descriptor | La-related protein 1, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE (3 entities in total) |
Functional Keywords | cap-binding, rna-binding, dm15, rna binding protein |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : Q6PKG0 |
Total number of polymer chains | 2 |
Total formula weight | 39771.78 |
Authors | Berman, A.J.,Lahr, R.M. (deposition date: 2017-03-10, release date: 2017-04-19, Last modification date: 2023-10-04) |
Primary citation | Lahr, R.M.,Fonseca, B.D.,Ciotti, G.E.,Al-Ashtal, H.A.,Jia, J.J.,Niklaus, M.R.,Blagden, S.P.,Alain, T.,Berman, A.J. La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs. Elife, 6:-, 2017 Cited by PubMed: 28379136DOI: 10.7554/eLife.24146 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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