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5V4R

Crystal structure of LARP1-unique domain DM15 bound to m7GTP

Summary for 5V4R
Entry DOI10.2210/pdb5v4r/pdb
DescriptorLa-related protein 1, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE (3 entities in total)
Functional Keywordscap-binding, rna-binding, dm15, rna binding protein
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm : Q6PKG0
Total number of polymer chains2
Total formula weight39771.78
Authors
Berman, A.J.,Lahr, R.M. (deposition date: 2017-03-10, release date: 2017-04-19, Last modification date: 2023-10-04)
Primary citationLahr, R.M.,Fonseca, B.D.,Ciotti, G.E.,Al-Ashtal, H.A.,Jia, J.J.,Niklaus, M.R.,Blagden, S.P.,Alain, T.,Berman, A.J.
La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
Elife, 6:-, 2017
Cited by
PubMed: 28379136
DOI: 10.7554/eLife.24146
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.77 Å)
Structure validation

221051

数据于2024-06-12公开中

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