5V4L
Cryptococcus neoformans adenylosuccinate lyase
Summary for 5V4L
Entry DOI | 10.2210/pdb5v4l/pdb |
Descriptor | Adenylosuccinate lyase (2 entities in total) |
Functional Keywords | lyase, fumerase, adenylosuccinate, saicar |
Biological source | Cryptococcus neoformans |
Total number of polymer chains | 4 |
Total formula weight | 214849.42 |
Authors | Chitty, J.,Williams, S.J.,Kobe, B.,Fraser, J.A. (deposition date: 2017-03-09, release date: 2017-06-07, Last modification date: 2023-10-04) |
Primary citation | Chitty, J.L.,Blake, K.L.,Blundell, R.D.,Koh, Y.Q.A.E.,Thompson, M.,Robertson, A.A.B.,Butler, M.S.,Cooper, M.A.,Kappler, U.,Williams, S.J.,Kobe, B.,Fraser, J.A. Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design. J. Biol. Chem., 292:11829-11839, 2017 Cited by PubMed: 28559277DOI: 10.1074/jbc.M117.787994 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report