5V4K

Crystal structure of NEDD4 LIR-fused human LC3B_2-119

5V4K の概要

• エントリーDOI: 10.2210/pdb5v4k/pdb
• 分子名称: Microtubule-associated proteins 1A/1B light chain 3B,Microtubule-associated proteins 1A/1B light chain 3B,Microtubule-associated proteins 1A/1B light chain 3B, GLYCEROL, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: autophagy, ubiquitin e3 ligase, hect, lir, lc3, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton: Q9GZQ8
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 31309.42

構造登録者

Qiu, Y.,Zheng, Y.,Schulman, B. (登録日: 2017-03-09, 公開日: 2017-05-17, 最終更新日: 2024-05-22)

• 主引用文献: Qiu, Y.,Zheng, Y.,Wu, K.P.,Schulman, B.A.; Insights into links between autophagy and the ubiquitin system from the structure of LC3B bound to the LIR motif from the E3 ligase NEDD4.; Protein Sci., 26:1674-1680, 2017; PubMed: 28470758; DOI: 10.1002/pro.3186

実験手法

X-RAY DIFFRACTION (2.099 Å)