5V4H

Ruthenium(II)(cymene)(chlorido)2-lysozyme adduct formed when ruthenium(II)(cymene)(bromido)2 underwent ligand exchange, resulting in one binding site

5V4H の概要

• エントリーDOI: 10.2210/pdb5v4h/pdb
• 関連するPDBエントリー: 5V4G 5V4I
• 分子名称: Lysozyme C, SODIUM ION, PARA-CYMENE RUTHENIUM CHLORIDE, ... (4 entities in total)
• 機能のキーワード: metal-based, anticancer, ruthenium, lysozyme, hydrolase
• 由来する生物種: Gallus gallus (Chicken)
• 細胞内の位置: Secreted: P00698
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14660.34

構造登録者

Sullivan, M.P.,Hartinger, C.G.,Goldstone, D.C. (登録日: 2017-03-09, 公開日: 2017-04-05, 最終更新日: 2023-10-04)

• 主引用文献: Sullivan, M.P.,Groessl, M.,Meier, S.M.,Kingston, R.L.,Goldstone, D.C.,Hartinger, C.G.; The metalation of hen egg white lysozyme impacts protein stability as shown by ion mobility mass spectrometry, differential scanning calorimetry, and X-ray crystallography.; Chem. Commun. (Camb.), 53:4246-4249, 2017; PubMed: 28361137; DOI: 10.1039/c6cc10150j

実験手法

X-RAY DIFFRACTION (1.22 Å)