5V44

Crystal structure of the SR1 domain of human sacsin

Summary for 5V44

• Entry DOI: 10.2210/pdb5v44/pdb
• Related: 5V45 5V46 5V47
• Descriptor: Sacsin, GLYCEROL (3 entities in total)
• Functional Keywords: alpha-beta sandwich, bergerat fold, chaperone
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 86462.95

Authors

Menade, M.,Kozlov, G.,Gehring, K. (deposition date: 2017-03-08, release date: 2017-05-24, Last modification date: 2023-11-15)

• Primary citation: Menade, M.,Kozlov, G.,Trempe, J.F.,Pande, H.,Shenker, S.,Wickremasinghe, S.,Li, X.,Hojjat, H.,Dicaire, M.J.,Brais, B.,McPherson, P.S.,Wong, M.J.H.,Young, J.C.,Gehring, K.; Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.; J. Biol. Chem., 293:12832-12842, 2018; PubMed: 29945973; DOI: 10.1074/jbc.RA118.003939

Experimental method

X-RAY DIFFRACTION (1.56 Å)