5V2P
CaV beta2a subunit: CaV1.2 AID-CAP complex
Summary for 5V2P
Entry DOI | 10.2210/pdb5v2p/pdb |
Related | 5V2Q |
Descriptor | Voltage-dependent L-type calcium channel subunit beta-2, Voltage-dependent L-type calcium channel subunit alpha-1C, NICKEL (II) ION, ... (6 entities in total) |
Functional Keywords | ion channel, signaling, calcium, transport protein |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 2 |
Total formula weight | 42171.30 |
Authors | Findeisen, F.,Campiglio, M.,Jo, H.,Rumpf, C.H.,Pope, L.,Flucher, B.,Degrado, W.F.,Minor, D.L. (deposition date: 2017-03-06, release date: 2017-07-19, Last modification date: 2023-10-04) |
Primary citation | Findeisen, F.,Campiglio, M.,Jo, H.,Abderemane-Ali, F.,Rumpf, C.H.,Pope, L.,Rossen, N.D.,Flucher, B.E.,DeGrado, W.F.,Minor, D.L. Stapled Voltage-Gated Calcium Channel (CaV) alpha-Interaction Domain (AID) Peptides Act As Selective Protein-Protein Interaction Inhibitors of CaV Function. ACS Chem Neurosci, 8:1313-1326, 2017 Cited by PubMed: 28278376DOI: 10.1021/acschemneuro.6b00454 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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