5V2I

Crystal structure of a mutant glycosylasparaginase (G172D) that causes the genetic disease Aspartylglucosaminuria

5V2I の概要

• エントリーDOI: 10.2210/pdb5v2i/pdb
• 分子名称: Glycosylasparaginase (2 entities in total)
• 機能のキーワード: beta-aha, catalytic mechanism, hydrolase
• 由来する生物種: Elizabethkingia meningoseptica
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 64475.34

構造登録者

Pande, S.,Guo, H. (登録日: 2017-03-04, 公開日: 2017-05-17, 最終更新日: 2023-10-04)

• 主引用文献: Pande, S.,Lakshminarasimhan, D.,Guo, H.C.; Crystal structure of a mutant glycosylasparaginase shedding light on aspartylglycosaminuria-causing mechanism as well as on hydrolysis of non-chitobiose substrate.; Mol. Genet. Metab., 121:150-156, 2017; PubMed: 28457719; DOI: 10.1016/j.ymgme.2017.04.008

実験手法

X-RAY DIFFRACTION (1.83 Å)