5V0X

Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001114

Summary for 5V0X

• Entry DOI: 10.2210/pdb5v0x/pdb
• Related: 5v0w
• Descriptor: Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA, {4-[2-(5-fluoro-2-{3-[(methylamino)methyl][1,2,4]triazolo[4,3-a]pyridin-6-yl}phenoxy)ethyl]-1,5-dimethyl-1H-pyrazol-3-yl}(morpholin-4-yl)methanone, ... (6 entities in total)
• Functional Keywords: ssgcid, glycylpeptide n-tetradecanoyltransferase, n-myristoyltransferase, nmt, plasmodium vival, salvador i, structural genomics, seattle structural genomics center for infectious disease, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Plasmodium vivax
• Total number of polymer chains: 3
• Total formula weight: 147948.61

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2017-02-28, release date: 2018-03-07, Last modification date: 2023-10-04)

• Primary citation: Mayclin, S.J.,Abendroth, J.,Lorimer, D.D.,Edwards, T.E.; Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001114; to be published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)