5V0X

Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001114

5V0X の概要

• エントリーDOI: 10.2210/pdb5v0x/pdb
• 関連するPDBエントリー: 5v0w
• 分子名称: Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA, {4-[2-(5-fluoro-2-{3-[(methylamino)methyl][1,2,4]triazolo[4,3-a]pyridin-6-yl}phenoxy)ethyl]-1,5-dimethyl-1H-pyrazol-3-yl}(morpholin-4-yl)methanone, ... (6 entities in total)
• 機能のキーワード: ssgcid, glycylpeptide n-tetradecanoyltransferase, n-myristoyltransferase, nmt, plasmodium vival, salvador i, structural genomics, seattle structural genomics center for infectious disease, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Plasmodium vivax
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 147948.61

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2017-02-28, 公開日: 2018-03-07, 最終更新日: 2023-10-04)

• 主引用文献: Mayclin, S.J.,Abendroth, J.,Lorimer, D.D.,Edwards, T.E.; Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001114; to be published,

実験手法

X-RAY DIFFRACTION (2.1 Å)