5V07
Crystal structure of human exonuclease 1 Exo1 (D173A) in complex with 5' recessed-end DNA (rV)
Summary for 5V07
Entry DOI | 10.2210/pdb5v07/pdb |
Related | 5UZV 5V04 5V05 5V06 5V08 5V09 5V0A 5V0B 5V0C 5V0D 5V0E |
Descriptor | Exonuclease 1, DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), ... (6 entities in total) |
Functional Keywords | exonuclease, endonuclease, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 46755.24 |
Authors | Shi, Y.,Beese, L.S. (deposition date: 2017-02-28, release date: 2017-05-24, Last modification date: 2023-10-04) |
Primary citation | Shi, Y.,Hellinga, H.W.,Beese, L.S. Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114:6010-6015, 2017 Cited by PubMed: 28533382DOI: 10.1073/pnas.1704845114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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