5UXQ

Structure of anti-HIV trimer apex antibody PGT143

Summary for 5UXQ

• Entry DOI: 10.2210/pdb5uxq/pdb
• Descriptor: PGT143 Fab Heavy Chain, PGT143 Fab Light Chain (3 entities in total)
• Functional Keywords: immunology, vaccine, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 4
• Total formula weight: 99811.26

Authors

Kong, L.,Wilson, I.A. (deposition date: 2017-02-23, release date: 2017-04-19, Last modification date: 2019-12-11)

• Primary citation: Lee, J.-H.,Andrabi, R.,Su, C.-Y.,Yasmeen, A.,Julien, J.-P.,Kong, L.,Wu, N.C.,McBride, R.,Sok, D.,Pauthner, M.,Cotrell, C.A.,Nieusma, T.,Blattner, C.,Paulson, J.C.,Klasee, P.J.,Wilson, I.A.,Burton, D.R.,Ward, A.B.; A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic Beta-Hairpin Structure; Immunity, 46:1-13, 2017

Experimental method

X-RAY DIFFRACTION (2.415 Å)