5UXQ
Structure of anti-HIV trimer apex antibody PGT143
Summary for 5UXQ
Entry DOI | 10.2210/pdb5uxq/pdb |
Descriptor | PGT143 Fab Heavy Chain, PGT143 Fab Light Chain (3 entities in total) |
Functional Keywords | immunology, vaccine, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 4 |
Total formula weight | 99811.26 |
Authors | Kong, L.,Wilson, I.A. (deposition date: 2017-02-23, release date: 2017-04-19, Last modification date: 2019-12-11) |
Primary citation | Lee, J.-H.,Andrabi, R.,Su, C.-Y.,Yasmeen, A.,Julien, J.-P.,Kong, L.,Wu, N.C.,McBride, R.,Sok, D.,Pauthner, M.,Cotrell, C.A.,Nieusma, T.,Blattner, C.,Paulson, J.C.,Klasee, P.J.,Wilson, I.A.,Burton, D.R.,Ward, A.B. A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic Beta-Hairpin Structure Immunity, 46:1-13, 2017 |
Experimental method | X-RAY DIFFRACTION (2.415 Å) |
Structure validation
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