5UUH

Bacillus cereus DNA glycosylase AlkD bound to a yatakemycin-adenine nucleobase adduct and DNA containing a fluorinated abasic site (9-mer product complex)

Summary for 5UUH

• Entry DOI: 10.2210/pdb5uuh/pdb
• Related: 5UUF 5UUG 5UUJ
• Descriptor: DNA-7-methylguanine glycosylase, DNA (5'-D(*AP*GP*GP*CP*AP*(ORF)P*AP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*TP*GP*CP*C)-3'), ... (6 entities in total)
• Functional Keywords: dna glycosylase, protein-dna complex, alkylpurine, bulky lesion, hydrolase-dna-antibiotic complex, hydrolase/dna/antibiotic
• Biological source: Bacillus cereus; More
• Total number of polymer chains: 3
• Total formula weight: 34805.45

Authors

Mullins, E.A.,Eichman, B.F. (deposition date: 2017-02-16, release date: 2017-07-19, Last modification date: 2023-10-04)

• Primary citation: Mullins, E.A.,Shi, R.,Eichman, B.F.; Toxicity and repair of DNA adducts produced by the natural product yatakemycin.; Nat. Chem. Biol., 13:1002-1008, 2017; PubMed: 28759018; DOI: 10.1038/nchembio.2439

Experimental method

X-RAY DIFFRACTION (1.569 Å)