5UTI
Crystal Structure of TGT in complex with fragment in preQ1 pocket
Summary for 5UTI
| Entry DOI | 10.2210/pdb5uti/pdb |
| Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total) |
| Functional Keywords | tgt, trna, guanine exchange enzyme, transferase, preq1 pocket, guanine pocket |
| Biological source | Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 |
| Total number of polymer chains | 1 |
| Total formula weight | 42427.60 |
| Authors | Hassaan, E.,Heine, A.,Klebe, G. (deposition date: 2017-02-15, release date: 2018-03-07, Last modification date: 2024-01-17) |
| Primary citation | Hassaan, E.,Eriksson, P.O.,Geschwindner, S.,Heine, A.,Klebe, G. Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies. Chemmedchem, 15:324-337, 2020 Cited by PubMed: 31808981DOI: 10.1002/cmdc.201900604 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.36 Å) |
Structure validation
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