5URQ

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p176

Summary for 5URQ

• Entry DOI: 10.2210/pdb5urq/pdb
• Related: 4MZ1 4MZ8 4R7J 5UQF 5UQG 5UQH
• Descriptor: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-alpha-D-ribofuranosylamine, ... (5 entities in total)
• Functional Keywords: impdh, tim barrel, delta cbs, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Campylobacter jejuni subsp. jejuni; More
• Total number of polymer chains: 8
• Total formula weight: 355104.71

Authors

Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2017-02-12, release date: 2017-03-01, Last modification date: 2023-10-04)

• Primary citation: Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID); Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p176; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)