5UP4
Structure of the HIV-1 Capsid Protein and spacer peptide 1 by Cryo-EM
Summary for 5UP4
Entry DOI | 10.2210/pdb5up4/pdb |
EMDB information | 8582 |
Descriptor | HIV-1 Capsid Protein and spacer peptide 1 (1 entity in total) |
Functional Keywords | hiv-1, spacer peptide 1, capsid protein, cryoem, helical assembly, reconstruction, virus |
Biological source | Human immunodeficiency virus 1 |
Cellular location | Host cytoplasm . Host nucleus . Matrix protein p17: Virion . Virion : B6DRA0 |
Total number of polymer chains | 18 |
Total formula weight | 443776.82 |
Authors | Perilla, J.R.,Schirra, R.,Zhang, P.,Schulten, K. (deposition date: 2017-02-01, release date: 2017-12-06, Last modification date: 2017-12-13) |
Primary citation | Wang, M.,Quinn, C.M.,Perilla, J.R.,Zhang, H.,Shirra, R.,Hou, G.,Byeon, I.J.,Suiter, C.L.,Ablan, S.,Urano, E.,Nitz, T.J.,Aiken, C.,Freed, E.O.,Zhang, P.,Schulten, K.,Gronenborn, A.M.,Polenova, T. Quenching protein dynamics interferes with HIV capsid maturation. Nat Commun, 8:1779-1779, 2017 Cited by PubMed: 29176596DOI: 10.1038/s41467-017-01856-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (9 Å) |
Structure validation
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