5UN9
The crystal structure of human O-GlcNAcase in complex with Thiamet-G
Summary for 5UN9
Entry DOI | 10.2210/pdb5un9/pdb |
Related | 5UN8 |
Descriptor | Protein O-GlcNAcase, (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL (3 entities in total) |
Functional Keywords | human o-glcnacase, thiemat-g, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Isoform 3: Nucleus . Isoform 1: Cytoplasm : O60502 |
Total number of polymer chains | 2 |
Total formula weight | 116143.73 |
Authors | |
Primary citation | Li, B.,Li, H.,Lu, L.,Jiang, J. Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode. Nat. Struct. Mol. Biol., 24:362-369, 2017 Cited by PubMed: 28319083DOI: 10.1038/nsmb.3390 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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