5UMK
Crystal structure of H62Y mutant of human macrophage migration inhibitory factor
Summary for 5UMK
| Entry DOI | 10.2210/pdb5umk/pdb |
| Related | 5UMJ |
| Descriptor | Macrophage migration inhibitory factor, SULFATE ION, ISOPROPYL ALCOHOL, ... (5 entities in total) |
| Functional Keywords | isomerase, trimeric, mutation |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 3 |
| Total formula weight | 37756.94 |
| Authors | Pantouris, G.,Lolis, E. (deposition date: 2017-01-27, release date: 2018-02-07, Last modification date: 2023-10-04) |
| Primary citation | Pantouris, G.,Khurana, L.,Ma, A.,Skeens, E.,Reiss, K.,Batista, V.S.,Lisi, G.P.,Lolis, E.J. Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27:740-750.e5, 2020 Cited by PubMed: 32433911DOI: 10.1016/j.chembiol.2020.05.001 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
Download full validation report
