5UM6

Crystal Structure of S. pombe Uba1 in a closed conformation

5UM6 の概要

• エントリーDOI: 10.2210/pdb5um6/pdb
• 分子名称: Ubiquitin-activating enzyme E1 1, SULFATE ION, N-(2-{[(4-chlorophenyl)methyl]disulfanyl}ethyl)decan-1-amine, ... (4 entities in total)
• 機能のキーワード: rossmann-like fold, ubiquitin-like fold, ubiquitin activating enzyme, atp binding, ligase activity, atp/mg binding, ubiquitin e2 binding, ligase, transferase, ligase-ligase inhibitor complex, ligase/ligase inhibitor
• 由来する生物種: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 112332.43

構造登録者

Lv, Z.,Yuan, L.,Aldana-Masangkay, G.,Atkison, J.H.,Chen, Y.,Olsen, S.K. (登録日: 2017-01-26, 公開日: 2017-06-14, 最終更新日: 2023-10-04)

• 主引用文献: Lv, Z.,Yuan, L.,Atkison, J.H.,Aldana-Masangkay, G.,Chen, Y.,Olsen, S.K.; Domain alternation and active site remodeling are conserved structural features of ubiquitin E1.; J. Biol. Chem., 292:12089-12099, 2017; PubMed: 28572513; DOI: 10.1074/jbc.M117.787622

実験手法

X-RAY DIFFRACTION (2.794 Å)